After a spending 40 years at Tufts University, Dr. Theoharides assumed a new position on July 1 as Professor at the Institute of Neuro-Immune Medicine at Nova Southeastern Univesrity in Clearwater, FL.
See contributions by Dr. Theoharides
1. Autism Parenting Summit Lecture:
How Inflammation Alters the Fear Center in the Brain and Affects Behavior in Autism
2. TACA conference on April 8-9 Lecture:
Your brain in autism and the spectrum of mast cell activation: from histamine intolerance to mastocytosis and everything in between.
The Centers for Disease Control (CDC) published in Morbidity and Mortality Weekly Report, its findings from the Autism and Developmental Disabilities Monitoring (ADDM) Network, an ongoing surveillance system that provides estimates on the prevalence of autism spectrum disorder (ASD), that 1 in 44 children in the U.S. have an autism diagnosis, a 10% increase from its 2018 report...
Still more research shows that many of the most common mental and physical conditions, including allergies and inflammation, may have a common somatic cause: mast cell over-activation. This insight may open unprecedented ways to understand and treat allergies, asthma, arthritis, cardiovascular diseases, psoriasis, dermatitis, cancer, endometriosis, and others such as Parkinson's disease, Alzheimer’s disease, ADHD or autism, chronic fatigue syndrome and Long-COVID syndrome. Discover how mast cell over-activation may drive autoimmune conditions, neuroinflammation, and a cascade of chemical imbalances in our bodies, significantly impacting our emotions and behaviors, and derailing our mind and body wellbeing.
Prof. Theoharis Theoharides, MSc, MPhil, PhD, MD has been invited to present a lecture entitled
SARS-CoV-2 spike protein, neuroinflammation and brain fog
at an all-NIH virtual conference
Unraveling Links Between Chronic Inflammation and Long COVID
Event Website: https://events.cancer.gov/nih/inflammation-long-covid
Registration Link: https://events.cancer.gov/nih/inflammation-long-covid/registration
Hashtags: #NCIEvent, #NCI, #LongCOVID, #LongCOVIDResearch, #LongCOVIDWorkshop, #LongHaulCOVID
DrTheoharides speaks at the 9-2023 NIH workshop on Neurologic Aspects of Long-COVID
Evidence indicates that post-acute sequelae of COVID-19 (PASC) or Long-COVID, is characterized by physical and mental fatigue that could be prevented or minimized by use of liposomal formulations of luteolin, such as in the novel supplement BrainGain (R) from www.algonot.com.
Learn More & Additional COVID Resources
Dr. Theoharides and his colleague Dr. Tsilioni reported for the first time that the Coronavirus Spike protein stimulates human mast cells to secrete proinflammatory molecules via the receptor TLR-4 and not the well-known receptor ACE2.
With thanks for help from Dr. Elizabeth Spaar, we put together these signs of shortness of breath you may look for in case someone is not able to communicate or is nonspeaking:
· Lethargy or unusual tiredness
· Panting or loud breathing
· Sucking in (retraction) at base of throat while inhaling
· Sucking in (retraction) at the ribs, also during inhale
· Belly breathing - seeing the stomach extended more than usual on inhale
· Stomach muscles tensing while trying to push air out
· Longer time to exhale than inhale
· Tripod stance (leaning over with hands on knees)
· Bluish nail beds or lips
· Change of mental status/confusion
If you develop emergency warning signs for COVID-19 get medical attention immediately. Emergency warning signs include:
· Difficulty breathing or shortness of breath
· Persistent pain or pressure in the chest
· New confusion or inability to arouse
· Bluish lips or face
More information can be found at the CDC's website
Pharmacology is the core of translational research leading to ways of alleviating disease. We study how mast cells are involved in allergy and inflammation. We showed that mast cells are activated by CRH and neurotensin secreted under stress to release inflammatory molecules selectively, including mitochondrial DNA ("innate pathogen") leading to disruption of the gut-blood-brain barriers and to inflammation. We have also shown that the flavonoid luteolin is inhibitory, and a patented liposomal formulation NeuroProtek®, benefits patients with allergies, autism and chronic fatigue syndrome...
MoreDonations for Center of Excellence for Neuroinflammation Research
Director: Prof. Theoharis Theoharides, MS, MPhil, PhD, MD
At Nova Southeastern University can be made in the following way:
Checks should be made out to:
Nova Southeastern University and reference
Index No. 337179- INIM Neuro-Inflammation R
