Pharmacology is the core of translational research leading to ways of alleviating disease. We study how mast cells are involved in allergy and inflammation. We showed that mast cells are activated by CRH and neurotensin secreted under stress to release inflammatory molecules selectively, including mitochondrial DNA ("innate pathogen") leading to disruption of the gut-blood-brain barriers and to inflammation. We have also shown that the flavonoid luteolin is inhibitory, and a patented liposomal formulation NeuroProtek®, benefits patients with allergies, autism and chronic fatigue syndrome.More
AUTISM - A Pharmacologist's View.
Learn more about T. C. Theoharides, MS, PhD, MD, FAAAAI
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T.C. Theoharides Ph.D., M.D.
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